Artículos de interés en PubMed

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Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities.

Simón J, Delgado TC, Martinez-Cruz LA, Martínez-Chantar ML.
Biomedicines. 2021 Jan 27;9(2):125. doi: 10.3390/biomedicines9020125.
PMID: 33513920 Review

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A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability.

Nikolaeva-Koleva M, Butron L, González-Rodríguez S, Devesa I, Valente P, Serafini M, Genazzani AA, Pirali T, Ballester GF, Fernández-Carvajal A, Ferrer-Montiel A.
Sci Rep. 2021 Jan 8;11(1):246. doi: 10.1038/s41598-020-80725-z.
PMID: 33420359

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Cross-Talk Between the Adenylyl Cyclase/cAMP Pathway and Ca2+ Homeostasis.

Sanchez-Collado J, Lopez JJ, Jardin I, Salido GM, Rosado JA.
Rev Physiol Biochem Pharmacol. 2021;179:73-116. doi: 10.1007/112_2020_55.
PMID: 33398503

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Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple negative breast cancer cells.

Jardin I, Diez-Bello R, Falcon D, Alvarado S, Regodon S, Salido GM, Smani T, Rosado JA.
J Biol Chem. 2020 Dec 30;296:100254. doi: 10.1074/jbc.RA120.015769. Online ahead of print.
PMID: 33380424

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PEG Equilibrium Partitioning in the α-Hemolysin Channel: Neutral Polymer Interaction with Channel Charges.

Aguilella-Arzo M, Aguilella VM.
Biomacromolecules. 2021 Feb 8;22(2):410-418. doi: 10.1021/acs.biomac.0c01286. Epub 2020 Dec 18.
PMID: 33337868

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PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca2+ Entry Via STIM2 in MDA-MB-231 Cells.

Cantonero C, Salido GM, Rosado JA, Redondo PC.
Int J Mol Sci. 2020 Oct 15;21(20):7641. doi: 10.3390/ijms21207641.
PMID: 33076541

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Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea.

Fernández-Trillo J, Florez-Paz D, Íñigo-Portugués A, González-González O, Del Campo AG, González A, Viana F, Belmonte C, Gomis A.
J Neurosci. 2020 Nov 18;40(47):8976-8993. doi: 10.1523/JNEUROSCI.0247-20.2020. Epub 2020 Oct 14.
PMID: 33055278

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Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels.

Fernández-Carvajal A, González-Muñiz R, Fernández-Ballester G, Ferrer-Montiel A.
Expert Opin Investig Drugs. 2020 Nov;29(11):1209-1222. doi: 10.1080/13543784.2020.1825680. Epub 2020 Sep 29.
PMID: 32941080 Review

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Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification.

Dionisi M, Ruffinatti FA, Riva B, Lim D, Canta A, Meregalli C, Fumagalli G, Monza L, Ferrer-Montiel A, Fernandez-Carvajal A, Cavaletti G, Genazzani AA, Distasi C.
Int J Mol Sci. 2020 Sep 28;21(19):7164. doi: 10.3390/ijms21197164.
PMID: 32998392

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Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities.

Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A.
Expert Opin Ther Targets. 2020 Nov;24(11):1079-1097. doi: 10.1080/14728222.2020.1820987. Epub 2020 Sep 24.
PMID: 32972264 Review

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